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You're viewing the Q4 2025 rate, effective October 2025 . See the current rate

HCPCS J3305

HCPCS Level II

Inj trimetrexate glucoronate

No national payment amount

Status E is not separately payable under the PFS.

Excluded from the PFS by regulation. Not payable under the PFS.

Common questions

Why is there no payment amount for J3305?

Its status indicator is E (excluded). Excluded from the PFS by regulation. Not payable under the PFS. The blank is deliberate: the amount is unknown or paid another way, not zero.

When does this rate change?

CMS publishes a fee schedule release every quarter (January, April, July, October). Each release is versioned here, so past quarters stay lookupable — see what changed each release, or get an email when a new release moves rates.

Sources: CMS Medicare Physician Fee Schedule Relative Value Files.

Saw this code on your bill?

What is a J3305 visit in patient-friendly terms?

In plain terms: Inj trimetrexate glucoronate You'll typically see HCPCS J3305 on a bill or explanation of benefits (EOB) when a clinician performs or bills for this service.

How this amount is computed

amount = (work RVU × work GPCI + PE RVU × PE GPCI + MP RVU × MP GPCI) × conversion factor. National amounts use GPCI = 1.000.

Release Q4 2025

Every rate combines three parts: work (the clinician’s time, skill and effort), practice expense (office overhead — higher when the service is done in a doctor’s own office), and malpractice (the share of liability-insurance cost). A value of blank means CMS publishes no national number for that part — which is not the same as zero.

Rate history by release

National non-facility amount for J3305 across quarterly releases.

$1 $1 $0 $-1 $-1 Q1 2025 · $0.00 Q2 2025 · $0.00 Q3 2025 · $0.00 Q4 2025 · $0.00 Q1 2025 Q2 2025 Q3 2025 Q4 2025
Non-facility Facility
Release Status Non-facility Facility
Q4 2025 Sep 11, 2025 E $0.00 $0.00
Q3 2025 Jun 5, 2025 E $0.00 $0.00
Q2 2025 Jun 5, 2025 E $0.00 $0.00

Source & method

Computed from the CMS Medicare Physician Fee Schedule Q4 2025 release (schedule pfs, effective October 2025). National amounts apply a GPCI of 1.000 and exclude sequestration. Payability follows the status indicator, not RVU values — blank RVUs are never treated as zero. Releases are immutable; a rate retrieved for a past quarter always reflects that release. Code descriptions for HCPCS Level II are CMS-owned.

Physician relative value file (Q4 2025) · 2025.zip (PPRRVU2025_Oct.csv row 16,807)

Conversion factor $32.3465 read from the same file, row 11, column 25.

Use the (i) buttons next to each amount above for the exact row, columns, and math.